CAS No.: 21535-47-7
盐酸米安色林 Catalog No. CSN10479
Synonyms: 盐酸米安色林;Org GB 94
Mianserin HCl is inverse agonist of H1 receptor and can be act as a psychoactive agent of the tetracyclic antidepressant.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00926835 Major Depressive Disorder Phase 4 Terminated(due to patient recr... more >>uitment difficulties) Collapse << - Korea, Republic of ... more >> Clinical research center for depression Seoul, Korea, Republic of, 150713 Collapse << NCT02336750 Breast Cancer Phase 3 Recruiting December 2019 China ... more >> Fudan University Cancer Hospital Recruiting Shanghai, China, 200032 Contact: Xichun Hu, MD,PhD 64175590 ext 5006 huxicun@gmail.com Contact: Jun Cao, MD 64175590 ext 5009 caojun1115lemon@163.com Collapse << NCT01764867 Major Depressive Disorder Phase 4 Unknown December 2014 China ... more >> Shanghai Mental Health Center Recruiting Shanghai, China, 200030 Contact: Zhiguo Wu, M.D. 862134289888 ext 3528 wu_zhiguo@yahoo.com.cn Principal Investigator: Yiru Fang, Ph.D., M.D. Collapse << - 更多
- 参考文献
- [1] Olianas MC, Dedoni S, et al. The atypical antidepressant mianserin exhibits agonist activity at κ-opioid receptors. Br J Pharmacol. 2012 Nov;167(6):1329-41.
- [2] de Boer TH, Nefkens F, et al. Differences in modulation of noradrenergic and serotonergic transmission by the alpha-2 adrenoceptor antagonists, mirtazapine, mianserin and idazoxan. J Pharmacol Exp Ther. 1996 May;277(2):852-60.
- [3] de Boer TH, Nefkens F, van Helvoirt A, van Delft AM. Differences in modulation of noradrenergic and serotonergic transmission by the alpha-2 adrenoceptor antagonists, mirtazapine, mianserin and idazoxan. J Pharmacol Exp Ther. 1996 May;277(2):852-60
- [4] Tanda G, Bassareo V, Di Chiara G. Mianserin markedly and selectively increases extracellular dopamine in the prefrontal cortex as compared to the nucleus accumbens of the rat. Psychopharmacology (Berl). 1996 Jan;123(2):127-30
- [5] Rocha B, Rigo M, Di Scala G, Sandner G, Hoyer D. Chronic mianserin or eltoprazine treatment in rats: effects on the elevated plus-maze test and on limbic 5-HT2C receptor levels. Eur J Pharmacol. 1994 Sep 1;262(1-2):125-31
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 21535-47-7 | 储存条件 |
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| 分子式 | C18H21ClN2 | 运输 | 蓝冰 | |||||||||
| 分子量 | 300.83 | 别名 | 盐酸米安色林;Org GB 94 | |||||||||
| 溶解度 |
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动物实验配方 |
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| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
|---|
| NCT00926835 | Major Depressive Disorder | Phase 4 | Terminated(due to patient recr... more >>uitment difficulties) Collapse << | - | Korea, Republic of ... more >> Clinical research center for depression Seoul, Korea, Republic of, 150713 Collapse << |
| NCT02336750 | Breast Cancer | Phase 3 | Recruiting | December 2019 | China ... more >> Fudan University Cancer Hospital Recruiting Shanghai, China, 200032 Contact: Xichun Hu, MD,PhD 64175590 ext 5006 huxicun@gmail.com Contact: Jun Cao, MD 64175590 ext 5009 caojun1115lemon@163.com Collapse << |
| NCT01764867 | Major Depressive Disorder | Phase 4 | Unknown | December 2014 | China ... more >> Shanghai Mental Health Center Recruiting Shanghai, China, 200030 Contact: Zhiguo Wu, M.D. 862134289888 ext 3528 wu_zhiguo@yahoo.com.cn Principal Investigator: Yiru Fang, Ph.D., M.D. Collapse << |
| NCT00590863 | Major Depressive Disorder | Phase 4 | Completed | - | United States, Alabama ... more >> Tuscalossa VA Mental Health Clinic Tuscaloosa, Alabama, United States, 35404 United States, California Harbor UCLA Family Health Care Center Harbor City, California, United States, 90710 UCLA Internal Medicine Clinic Los Angeles, California, United States, 90024 Veterans Affairs Medical Center/FIRM Primary Care Clinic San Diego, California, United States, 92161 United States, Illinois Northwestern Psychiatric Outpatient Treatment Care Center Chicago, Illinois, United States, 60611 United States, Kansas Clinical Research Institute Wichita, Kansas, United States, 67214 United States, Massachusetts MGH/Northshore Medical Center (Salem Psychiatric Facility) Salem, Massachusetts, United States, 01970 United States, Michigan General Psychiatric Ambulatory Clinic Ann Arbor, Michigan, United States, 48105 United States, New York Irving Goldman Primary Care at North Shore Hospital New York, New York, United States, 11040 United States, North Carolina UNC Chapel Hill Adult Diagnostic & Treatment Clinic Chapel Hill, North Carolina, United States, 27599-7160 United States, Oklahoma Laureate Psychiatric Clinic and Hospital Tulsa, Oklahoma, United States, 74135 United States, Pennsylvania Bellefield Clinic of WPIC Pittsburgh, Pennsylvania, United States, 15213 United States, Tennessee Vine Hill Community Clinic Nashville, Tennessee, United States, 37212 United States, Texas UT Southwestern Family Medicine Clinic Dallas, Texas, United States, 75390 United States, Virginia VCU Outpatient Psychiatry Clinic Richmond, Virginia, United States, 23298 Collapse << |
| NCT00590863 | - | - | Completed | - | - |
| NCT03148522 | Diagnosis and Treatment of Dep... more >>ression Collapse << | Phase 4 | Not yet recruiting | December 30, 2021 | - |
| NCT01725048 | Major Depressive Disorder ... more >> Neoplasms Collapse << | Early Phase 1 | Completed | - | United States, North Carolina ... more >> University of North Carolina Hospital Chapel Hill, North Carolina, United States, 27599 Collapse << |
| NCT03219008 | Depressive Disorder | Phase 4 | Recruiting | December 2020 | China ... more >> ShanghaiMHC Recruiting Shanghai, China Collapse << |
| NCT01109693 | Unipolar Major Depressive Epis... more >>ode Collapse << | Phase 4 | Completed | - | Japan ... more >> Nagoya City University Hospital Nagoya, Aichi, Japan, 467-8602 Kochi Medical School Hospital Nangoku, Kochi, Japan, 783-8505 Collapse << |
| NCT01465919 | Depression | Phase 4 | Terminated(Due to the recent c... more >>hange in standard of care for hepatitis C.) Collapse << | - | Korea, Republic of ... more >> SMG-SNU Boramae Medical Center Seoul, Korea, Republic of, 156-707 Collapse << |
| NCT03675555 | Shivering | Phase 4 | Completed | - | Egypt ... more >> Ibrahim Mamdouh Esmat Heliopolis, Cairo, Egypt, 11361 Collapse << |
| NCT00150839 | Depressive Disorder, Major | Phase 4 | Unknown | December 2009 | Germany ... more >> Department of Psychiatry and Psychotherapy, University Erlangen-Nuremberg Recruiting Erlangen, Bavaria, Germany, 91054 Contact: Stefan Bleich, MD 004991318534262 stefan.bleich@uk-erlangen.de Principal Investigator: Stefan Bleich, MD Sub-Investigator: Julia Wilhelm, MD Sub-Investigator: Helge Frieling, MD Collapse << |
| NCT01178671 | - | - | Completed | - | - |
| NCT01178671 | Posttraumatic Stress Disorder | Phase 4 | Completed | - | United States, New York ... more >> Anxiety Disorders Clinic, New York State Psychiatric Institute New York, New York, United States, 10032 Collapse << |
| NCT03283488 | Cachexia; Cancer ... more >> Anorexia Collapse << | Phase 3 | Not yet recruiting | December 30, 2020 | Brazil ... more >> Clinics Hospital, Ribeirão Preto Medical School, University of São Paulo Not yet recruiting Ribeirão Preto, São Paulo, Brazil, 14048900 Contact: Nereida KC Lima, MD, PhD +5516992770522 nereida@fmrp.usp.br Collapse << |
| NCT01263080 | Schizophrenia | Phase 4 | Completed | - | China, Beijing ... more >> Beijing Anding Hospital, Capital Medical University Beijing, Beijing, China, 100088 Collapse << |
| NCT01501396 | Anorexia | Phase 2 | Withdrawn | September 2015 | - |
| NCT00249444 | Cocaine Dependence ... more >> Depression Collapse << | Phase 2 | Completed | - | United States, New York ... more >> Research Foundation for Mental Hygiene, Inc. New York, New York, United States, 10032 Collapse << |
| NCT00249444 | - | - | Completed | - | - |
| NCT00322309 | - | - | Completed | - | - |
| NCT00497081 | - | - | Completed | - | - |
| NCT00497081 | Substance Abuse ... more >> HIV Infections Collapse << | Phase 2 | Completed | - | United States, California ... more >> San Francisco Department of Public Health, Substance Use Research Unit San Francisco, California, United States, 94102 Collapse << |
| NCT00782405 | Sleep | Phase 3 | Completed | - | Germany ... more >> Sleep Disorders Center Munich, Bavaria, Germany, 81675 Collapse << |
| NCT01165541 | - | - | Completed | - | - |
| NCT00322309 | Cocaine Dependence ... more >> Depression Collapse << | Phase 2 | Completed | - | United States, Massachusetts ... more >> Boston University Boston, Massachusetts, United States, 02118 Collapse << |
| NCT01165541 | Alcohol Dependence | Phase 2 | Completed | - | United States, New Hampshire ... more >> Dartmouth Medical School Department of Psychiatry's Addition Research Center Bedford, New Hampshire, United States, 03110 Dartmouth Medical School Department of Psychiatry's Addiction Research Center Hanover, New Hampshire, United States, 03755 Collapse << |
| NCT00874003 | Alcohol Dependence | Phase 2 | Completed | - | Sweden ... more >> Addiction Biology Unit Gothenburg, Sweden, 413 45 Collapse << |
| NCT01598584 | Pancreatic Cancer | Phase 2 Phase 3 | Withdrawn(Gemcitabine is not t... more >>he first choice for most pancreatic cancer patients nowdays) Collapse << | December 2015 | China, Tianjin ... more >> TianjinCIH Tianjin, Tianjin, China, 300060 Collapse << |
| NCT01888835 | Amphetamine-Related Disorders | Phase 2 | Completed | - | United States, California ... more >> Substance Use Research Unit San Francisco, California, United States, 94102 Collapse << |
| NCT01497548 | Depression | Phase 3 | Unknown | October 2012 | Malaysia ... more >> University Malaya Medical Centre Recruiting Kuala Lumpur, Malaysia, 50603 Contact: Chong Guan Ng, MBBS, MPM 0379492068 chong_guan1975@yahoo.co.uk University Malaya Medical Centre Not yet recruiting Kuala Lumpur, Malaysia, 59100 Contact: Chong Guan Ng, MBBS, MPM 60379604367 chong_guan@hotmail.com Principal Investigator: Chong Guan Ng, MBBS, MPM Collapse << |
| NCT00798395 | Sleep Initiation and Maintenan... more >>ce Disorders Mental Disorders Collapse << | Phase 1 | Completed | - | - |
| NCT02541526 | Heroin Dependence ... more >> Amphetamine Dependence Collapse << | Phase 3 | Unknown | May 2017 | Malaysia ... more >> University Science Malaysia Recruiting Kota bharu, Kelantan, Malaysia, 16010 Contact: Vicknasingam B Kasinather, PhD 6046532140 vickna@usm.my Contact: Imran Ahmad 6097676603 profimran@usm.my Collapse << |
| NCT00600145 | Amphetamine Dependence | Not Applicable | Withdrawn(PI decision) | July 2010 | United States, Virginia ... more >> Universiyt of Virginia Charlottesville, Virginia, United States, 22908 Collapse << |
| NCT03679052 | Shivering | Phase 4 | Completed | - | Egypt ... more >> Ibrahim Mamdouh Esmat Heliopolis, Cairo, Egypt, 11361 Collapse << |
| NCT02191124 | Major Depressive Disorder | Phase 4 | Completed | - | China, Beijing ... more >> Beijing Anding Hospital Beijing, Beijing, China, 100088 Collapse << |
| NCT01949571 | Drug-withdrawal. ... more >> Drug Abuse Drug-induced Depressive State AOD Craving AODR Depressive State Collapse << | Phase 2 | Completed | - | Mexico ... more >> National Institute of Psychiatry México. Distrito Federal, Distrito Federal, Mexico, 14370 Collapse << |
| NCT00288782 | Mental Disorders ... more >> Mood Disorders Affective Disorders Depressive Disorders Collapse << | Phase 4 | Completed | - | Denmark ... more >> Center for Psychiatric Research, Psychiatric Hospital of Aarhus University Risskov, Denmark, 8240 Collapse << |
| NCT02374567 | Dementia Depr... more >>ession Schizophrenia Psychosomatic Disorders Anxiety Disorders Collapse << | Phase 3 | Terminated | - | Germany ... more >> Bezirkskrankenhaus Augsburg Augsburg, Germany Krankenhaus Hedwigshöhe Berlin, Germany Hannover Medical School Hannover, Germany, 30625 Asklepios Fachklinikum Lübben Lübben, Germany Asklepios Fachklinikum Teupitz Teupitz, Germany Collapse << |
| NCT00302107 | Anxiety PTSD | Phase 4 | Completed | - | United States, Alabama ... more >> Tuscaloosa VAMC Tuscaloosa, Alabama, United States, 35405 Collapse << |
| NCT00302107 | - | - | Completed | - | - |
| NCT01458626 | Major Depression | Phase 4 | Completed | - | China, Beijing ... more >> Beijing Anding Hospital Beijing, Beijing, China, 100088 Collapse << |
| NCT01305707 | Depression | Phase 4 | Terminated(Difficulties in rec... more >>ruiting) Collapse << | - | Spain ... more >> Hospital Universitari de Bellvitge Hospitalet de Llobregat, Barcelona, Spain, 08907 Corporació Sanitària Parc Tauli Sabadell, Barcelona, Spain, 08208 Hospital Universitari de Bellvitge, IDIBELL Barcelona, Spain, 08907 Collapse << |
| NCT00488072 | Advanced Cancer ... more >> Anorexia Weight Loss Insomnia Collapse << | Phase 2 | Active, not recruiting | January 2020 | United States, Texas ... more >> University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
| NCT00506389 | Insomnia | Phase 3 | Completed | - | - |
| NCT00482612 | - | - | Completed | - | - |
| NCT00535288 | Postmenopausal Symptoms ... more >> Menopause Vasomotor Symptoms Collapse << | Phase 3 | Completed | - | - |
| NCT00482612 | Insomnia | Phase 3 | Completed | - | - |
| NCT00560833 | - | - | Completed | - | - |
| NCT00561574 | Sleep Initiation and Maintenan... more >>ce Disorder; Elderly Mental Disorder Dyssomnias Sleep Disorders Sleep Disorder, Intrinsic Collapse << | Phase 3 | Completed | - | - |
| NCT00506389 | - | - | Completed | - | - |
| NCT00561821 | Insomnia Slee... more >>p Initiation and Maintenance Disorders Mental Disorders Dyssomnias Sleep Disorders Collapse << | Phase 3 | Completed | - | - |
| NCT00535288 | - | - | Completed | - | - |
| NCT00561574 | - | - | Completed | - | - |
| NCT00560833 | Menopause Vas... more >>omotor Symptoms Collapse << | Phase 3 | Completed | - | - |
| NCT00561821 | - | - | Completed | - | - |
| NCT00631657 | Sleep Initiation and Maintenan... more >>ce Disorders Mental Disorders Dyssomnias Sleep Disorders Sleep Disorder, Intrinsic Collapse << | Phase 3 | Completed | - | - |
| NCT00750919 | - | - | Terminated(This trial was stop... more >>ped prematurely due to the Sponsor's decision not to continue the development of esmertazapine for this indication.) Collapse << | - | - |
| NCT00750919 | Sleep Initiation and Maintenan... more >>ce Disorders Mental Disorders Dyssomnias Sleep Disorders Sleep Disorders, Intrinsic Collapse << | Phase 3 | Terminated(This trial was stop... more >>ped prematurely due to the Sponsor's decision not to continue the development of esmertazapine for this indication.) Collapse << | - | - |
| NCT00832520 | Advanced Cancer | Phase 2 | Terminated(Low accrual rate.) | - | United States, New Mexico ... more >> University of New Mexico Cancer Center @ Lovelace Medical Center Albuquerque, New Mexico, United States, 87102 Universtiy of New Mexico - Cancer Center Albuquerque, New Mexico, United States, 87106 Collapse << |
| NCT00631657 | - | - | Completed | - | - |
| NCT00832520 | - | - | Terminated(Low accrual rate.) | - | - |
| NCT00834197 | Healthy | Phase 1 | Completed | - | United States, North Dakota ... more >> PRACS Institute, Ltd. Fargo, North Dakota, United States, 58104 Collapse << |
| NCT00610675 | Insomnia | Phase 3 | Completed | - | - |
| NCT00834197 | - | - | Completed | - | - |
| NCT00610675 | - | - | Completed | - | - |
| NCT00835575 | Healthy | Phase 1 | Completed | - | United States, North Dakota ... more >> PRACS Institute, Ltd. Fargo, North Dakota, United States, 58104 Collapse << |
| NCT00835575 | - | - | Completed | - | - |
| NCT00919295 | Fibromyalgia Syndrome | Phase 2 | Completed | - | Thailand ... more >> Siriraj Hospital, Mahidol University Bangkoknoi, Bangkok, Thailand, 10700 Collapse << |
| NCT01039740 | Depression | Not Applicable | Unknown | December 2018 | Korea, Republic of ... more >> Samsung Medical Center Recruiting Kangnam, Seoul, Korea, Republic of, 135-710 Contact: Samsung Medical Center Kim, phD, MD 82-2-3410-3582 dohkwan.kim@samsung.com Collapse << |
| NCT00878540 | Healthy | Phase 1 | Completed | - | Germany ... more >> Max Planck Institue of Psychiatry Munich, Germany Collapse << |
| NCT00865384 | Healthy | Phase 1 | Completed | - | United States, North Dakota ... more >> PRACS Institute, Ltd. Fargo, North Dakota, United States, 58102 Collapse << |
| NCT00865696 | Healthy | Phase 1 | Completed | - | United States, North Dakota ... more >> PRACS Institute, Ltd. Fargo, North Dakota, United States, 58102 Collapse << |
| NCT01119924 | Depression Pa... more >>in Collapse << | Phase 4 | Completed | - | Taiwan ... more >> Nang Kuang Pharmaceutical Co., LTD Tainan, Xinhua Township, Taiwan Collapse << |
| NCT01302964 | Autism Spectrum Disorders | Phase 3 | Completed | - | United States, Indiana ... more >> Riley Child and Adolescent Psychiatry Clinic Riley Hospital Indianapolis, Indiana, United States, 46202 United States, Massachusetts Lurie Center -MassGeneral Hospital Lexington, Massachusetts, United States, 02421 Collapse << |
| NCT01505504 | - | - | Completed | - | Belgium ... more >> CHU Brugmann Brussels, Belgium, 1020 Collapse << |
| NCT01302964 | - | - | Completed | - | - |
| NCT00960830 | Depression An... more >>xiety Collapse << | Not Applicable | Completed | - | Argentina ... more >> Cl Sn Nicol San Nicolas, Bs As, Argentina, 1900 Collapse << |
| NCT01867775 | Alzheimer's Disease ... more >> Sleep Disorders Collapse << | Phase 3 | Unknown | May 2014 | Brazil ... more >> Brasilia University Recruiting Brasilia, Distrito Federal, Brazil, 70840 Contact: Francisca M Scoralick franciscascoralick@gmail.com Sub-Investigator: Francisca M Scoralick Collapse << |
| NCT01601002 | Major Depressive Disorder | Phase 4 | Completed | - | Canada, Ontario ... more >> London Health Sciences Centre London, Ontario, Canada, N6A 5W9 Collapse << |
| NCT01240096 | Functional Dyspepsia | Phase 4 | Unknown | December 2011 | Belgium ... more >> University Hospitals Recruiting Leuven, Vlaanderen, Belgium, 3000 Contact: Jan Tack, M.D., Ph.D. +3216344225 jan.tack@med.kuleuven.be Principal Investigator: Jan Tack, M.D., Ph.D. Collapse << |
| NCT02185131 | - | - | Completed | - | - |
| NCT02185131 | Major Depressive Disorder ... more >> Alcohol Use Disorder Collapse << | Phase 2 | Completed | - | United States, Pennsylvania ... more >> Western Psychiatric Institute and Clinic Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
| NCT02646449 | Major Depressive Disorder ... more >> Alcohol Use Disorder Collapse << | Phase 2 | Completed | - | United States, Pennsylvania ... more >> Western Psychiatric Institute and Clinic Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
| NCT02650544 | Carcinoma, Non-Small-Cell Lung... more >> Depression Collapse << | Phase 2 | Active, not recruiting | June 2019 | China, Guangdong ... more >> Cancer Center of Sun-Yat Sen University (CCSYSU) GuangZhou, Guangdong, China, 510060 Collapse << |
| NCT01569685 | Post Traumatic Stress Disorder... more >> Depression Collapse << | Phase 4 | Completed | - | Denmark ... more >> Competence Center for Transcultural Psychiatry Gentofte, Denmark, 2900 Collapse << |
| NCT03031184 | Dementia | Phase 3 | Recruiting | July 2020 | United Kingdom ... more >> Sube Banerjee Recruiting Brighton, Sussex, United Kingdom, BN1 9RY Contact: Sube Banerjee, MD 01273877896 s.banerjee@bsms.ac.uk Principal Investigator: Naji Tabet, MD Principal Investigator: Chris Fox, MD Principal Investigator: Alan Thomas, MD Principal Investigator: Ross Dunne, MD Principal Investigator: Gill Livingston, MD Principal Investigator: Peter Bentham, MD Principal Investigator: Annabel Price, MD Principal Investigator: Ramin Nilforooshan, MD Principal Investigator: Carol Bannister, MD Principal Investigator: Sushanth Kamath, MD Collapse << |
| NCT00917397 | Post-Traumatic Stress Disorder | Phase 4 | Completed | - | Denmark ... more >> Psykiatrisk Center Gentofte Hellerup, Denmark, 2900 Collapse << |
| NCT02646449 | - | - | Completed | - | - |
| NCT02761161 | Post Traumatic Stress Disorder... more >> Depression Collapse << | Phase 4 | Active, not recruiting | March 2019 | Denmark ... more >> Competence Centre for Transcultural Psychiatry Copenhagen, Ballerup, Denmark, 2750 Collapse << |
| NCT02228239 | Healthy | Phase 1 | Completed | - | Netherlands ... more >> Leiden, Netherlands Collapse << |
| NCT03254173 | Advanced Cancer ... more >> Cancer Associated Anorexia - Cachexia Collapse << | Phase 2 Phase 3 | Not yet recruiting | August 1, 2018 | - |
| NCT00926835 | Major Depressive Disorder | Phase 4 | Terminated(due to patient recr... more >>uitment difficulties) Collapse << | - | Korea, Republic of ... more >> Clinical research center for depression Seoul, Korea, Republic of, 150713 Collapse << |
| NCT01764867 | Major Depressive Disorder | Phase 4 | Unknown | December 2014 | China ... more >> Shanghai Mental Health Center Recruiting Shanghai, China, 200030 Contact: Zhiguo Wu, M.D. 862134289888 ext 3528 wu_zhiguo@yahoo.com.cn Principal Investigator: Yiru Fang, Ph.D., M.D. Collapse << |
| NCT03219008 | Depressive Disorder | Phase 4 | Recruiting | December 2020 | China ... more >> ShanghaiMHC Recruiting Shanghai, China Collapse << |
| NCT00590863 | Major Depressive Disorder | Phase 4 | Completed | - | United States, Alabama ... more >> Tuscalossa VA Mental Health Clinic Tuscaloosa, Alabama, United States, 35404 United States, California Harbor UCLA Family Health Care Center Harbor City, California, United States, 90710 UCLA Internal Medicine Clinic Los Angeles, California, United States, 90024 Veterans Affairs Medical Center/FIRM Primary Care Clinic San Diego, California, United States, 92161 United States, Illinois Northwestern Psychiatric Outpatient Treatment Care Center Chicago, Illinois, United States, 60611 United States, Kansas Clinical Research Institute Wichita, Kansas, United States, 67214 United States, Massachusetts MGH/Northshore Medical Center (Salem Psychiatric Facility) Salem, Massachusetts, United States, 01970 United States, Michigan General Psychiatric Ambulatory Clinic Ann Arbor, Michigan, United States, 48105 United States, New York Irving Goldman Primary Care at North Shore Hospital New York, New York, United States, 11040 United States, North Carolina UNC Chapel Hill Adult Diagnostic & Treatment Clinic Chapel Hill, North Carolina, United States, 27599-7160 United States, Oklahoma Laureate Psychiatric Clinic and Hospital Tulsa, Oklahoma, United States, 74135 United States, Pennsylvania Bellefield Clinic of WPIC Pittsburgh, Pennsylvania, United States, 15213 United States, Tennessee Vine Hill Community Clinic Nashville, Tennessee, United States, 37212 United States, Texas UT Southwestern Family Medicine Clinic Dallas, Texas, United States, 75390 United States, Virginia VCU Outpatient Psychiatry Clinic Richmond, Virginia, United States, 23298 Collapse << |
| NCT01725048 | Major Depressive Disorder ... more >> Neoplasms Collapse << | Early Phase 1 | Completed | - | United States, North Carolina ... more >> University of North Carolina Hospital Chapel Hill, North Carolina, United States, 27599 Collapse << |
| NCT00590863 | - | - | Completed | - | - |
| NCT02336750 | Breast Cancer | Phase 3 | Recruiting | December 2019 | China ... more >> Fudan University Cancer Hospital Recruiting Shanghai, China, 200032 Contact: Xichun Hu, MD,PhD 64175590 ext 5006 huxicun@gmail.com Contact: Jun Cao, MD 64175590 ext 5009 caojun1115lemon@163.com Collapse << |
| NCT01263080 | Schizophrenia | Phase 4 | Completed | - | China, Beijing ... more >> Beijing Anding Hospital, Capital Medical University Beijing, Beijing, China, 100088 Collapse << |
| NCT03148522 | Diagnosis and Treatment of Dep... more >>ression Collapse << | Phase 4 | Not yet recruiting | December 30, 2021 | - |
| NCT03675555 | Shivering | Phase 4 | Completed | - | Egypt ... more >> Ibrahim Mamdouh Esmat Heliopolis, Cairo, Egypt, 11361 Collapse << |
| NCT01178671 | Posttraumatic Stress Disorder | Phase 4 | Completed | - | United States, New York ... more >> Anxiety Disorders Clinic, New York State Psychiatric Institute New York, New York, United States, 10032 Collapse << |
| NCT01465919 | Depression | Phase 4 | Terminated(Due to the recent c... more >>hange in standard of care for hepatitis C.) Collapse << | - | Korea, Republic of ... more >> SMG-SNU Boramae Medical Center Seoul, Korea, Republic of, 156-707 Collapse << |
| NCT01178671 | - | - | Completed | - | - |
| NCT01501396 | Anorexia | Phase 2 | Withdrawn | September 2015 | - |
| NCT00150839 | Depressive Disorder, Major | Phase 4 | Unknown | December 2009 | Germany ... more >> Department of Psychiatry and Psychotherapy, University Erlangen-Nuremberg Recruiting Erlangen, Bavaria, Germany, 91054 Contact: Stefan Bleich, MD 004991318534262 stefan.bleich@uk-erlangen.de Principal Investigator: Stefan Bleich, MD Sub-Investigator: Julia Wilhelm, MD Sub-Investigator: Helge Frieling, MD Collapse << |
| NCT03283488 | Cachexia; Cancer ... more >> Anorexia Collapse << | Phase 3 | Not yet recruiting | December 30, 2020 | Brazil ... more >> Clinics Hospital, Ribeirão Preto Medical School, University of São Paulo Not yet recruiting Ribeirão Preto, São Paulo, Brazil, 14048900 Contact: Nereida KC Lima, MD, PhD +5516992770522 nereida@fmrp.usp.br Collapse << |
| NCT01109693 | Unipolar Major Depressive Epis... more >>ode Collapse << | Phase 4 | Completed | - | Japan ... more >> Nagoya City University Hospital Nagoya, Aichi, Japan, 467-8602 Kochi Medical School Hospital Nangoku, Kochi, Japan, 783-8505 Collapse << |
| NCT00249444 | Cocaine Dependence ... more >> Depression Collapse << | Phase 2 | Completed | - | United States, New York ... more >> Research Foundation for Mental Hygiene, Inc. New York, New York, United States, 10032 Collapse << |
| NCT00249444 | - | - | Completed | - | - |
| NCT00322309 | Cocaine Dependence ... more >> Depression Collapse << | Phase 2 | Completed | - | United States, Massachusetts ... more >> Boston University Boston, Massachusetts, United States, 02118 Collapse << |
| NCT00322309 | - | - | Completed | - | - |
| NCT00497081 | - | - | Completed | - | - |
| NCT00497081 | Substance Abuse ... more >> HIV Infections Collapse << | Phase 2 | Completed | - | United States, California ... more >> San Francisco Department of Public Health, Substance Use Research Unit San Francisco, California, United States, 94102 Collapse << |
| NCT00600145 | Amphetamine Dependence | Not Applicable | Withdrawn(PI decision) | July 2010 | United States, Virginia ... more >> Universiyt of Virginia Charlottesville, Virginia, United States, 22908 Collapse << |
| NCT01165541 | - | - | Completed | - | - |
| NCT00798395 | Sleep Initiation and Maintenan... more >>ce Disorders Mental Disorders Collapse << | Phase 1 | Completed | - | - |
| NCT00782405 | Sleep | Phase 3 | Completed | - | Germany ... more >> Sleep Disorders Center Munich, Bavaria, Germany, 81675 Collapse << |
| NCT01497548 | Depression | Phase 3 | Unknown | October 2012 | Malaysia ... more >> University Malaya Medical Centre Recruiting Kuala Lumpur, Malaysia, 50603 Contact: Chong Guan Ng, MBBS, MPM 0379492068 chong_guan1975@yahoo.co.uk University Malaya Medical Centre Not yet recruiting Kuala Lumpur, Malaysia, 59100 Contact: Chong Guan Ng, MBBS, MPM 60379604367 chong_guan@hotmail.com Principal Investigator: Chong Guan Ng, MBBS, MPM Collapse << |
| NCT00874003 | Alcohol Dependence | Phase 2 | Completed | - | Sweden ... more >> Addiction Biology Unit Gothenburg, Sweden, 413 45 Collapse << |
| NCT01598584 | Pancreatic Cancer | Phase 2 Phase 3 | Withdrawn(Gemcitabine is not t... more >>he first choice for most pancreatic cancer patients nowdays) Collapse << | December 2015 | China, Tianjin ... more >> TianjinCIH Tianjin, Tianjin, China, 300060 Collapse << |
| NCT01949571 | Drug-withdrawal. ... more >> Drug Abuse Drug-induced Depressive State AOD Craving AODR Depressive State Collapse << | Phase 2 | Completed | - | Mexico ... more >> National Institute of Psychiatry México. Distrito Federal, Distrito Federal, Mexico, 14370 Collapse << |
| NCT01165541 | Alcohol Dependence | Phase 2 | Completed | - | United States, New Hampshire ... more >> Dartmouth Medical School Department of Psychiatry's Addition Research Center Bedford, New Hampshire, United States, 03110 Dartmouth Medical School Department of Psychiatry's Addiction Research Center Hanover, New Hampshire, United States, 03755 Collapse << |
| NCT01888835 | Amphetamine-Related Disorders | Phase 2 | Completed | - | United States, California ... more >> Substance Use Research Unit San Francisco, California, United States, 94102 Collapse << |
| NCT01458626 | Major Depression | Phase 4 | Completed | - | China, Beijing ... more >> Beijing Anding Hospital Beijing, Beijing, China, 100088 Collapse << |
| NCT02191124 | Major Depressive Disorder | Phase 4 | Completed | - | China, Beijing ... more >> Beijing Anding Hospital Beijing, Beijing, China, 100088 Collapse << |
| NCT03679052 | Shivering | Phase 4 | Completed | - | Egypt ... more >> Ibrahim Mamdouh Esmat Heliopolis, Cairo, Egypt, 11361 Collapse << |
| NCT01305707 | Depression | Phase 4 | Terminated(Difficulties in rec... more >>ruiting) Collapse << | - | Spain ... more >> Hospital Universitari de Bellvitge Hospitalet de Llobregat, Barcelona, Spain, 08907 Corporació Sanitària Parc Tauli Sabadell, Barcelona, Spain, 08208 Hospital Universitari de Bellvitge, IDIBELL Barcelona, Spain, 08907 Collapse << |
| NCT00288782 | Mental Disorders ... more >> Mood Disorders Affective Disorders Depressive Disorders Collapse << | Phase 4 | Completed | - | Denmark ... more >> Center for Psychiatric Research, Psychiatric Hospital of Aarhus University Risskov, Denmark, 8240 Collapse << |
| NCT00302107 | Anxiety PTSD | Phase 4 | Completed | - | United States, Alabama ... more >> Tuscaloosa VAMC Tuscaloosa, Alabama, United States, 35405 Collapse << |
| NCT02541526 | Heroin Dependence ... more >> Amphetamine Dependence Collapse << | Phase 3 | Unknown | May 2017 | Malaysia ... more >> University Science Malaysia Recruiting Kota bharu, Kelantan, Malaysia, 16010 Contact: Vicknasingam B Kasinather, PhD 6046532140 vickna@usm.my Contact: Imran Ahmad 6097676603 profimran@usm.my Collapse << |
| NCT00488072 | Advanced Cancer ... more >> Anorexia Weight Loss Insomnia Collapse << | Phase 2 | Active, not recruiting | January 2020 | United States, Texas ... more >> University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
| NCT00482612 | Insomnia | Phase 3 | Completed | - | - |
| NCT02374567 | Dementia Depr... more >>ession Schizophrenia Psychosomatic Disorders Anxiety Disorders Collapse << | Phase 3 | Terminated | - | Germany ... more >> Bezirkskrankenhaus Augsburg Augsburg, Germany Krankenhaus Hedwigshöhe Berlin, Germany Hannover Medical School Hannover, Germany, 30625 Asklepios Fachklinikum Lübben Lübben, Germany Asklepios Fachklinikum Teupitz Teupitz, Germany Collapse << |
| NCT00506389 | - | - | Completed | - | - |
| NCT00302107 | - | - | Completed | - | - |
| NCT00482612 | - | - | Completed | - | - |
| NCT00560833 | Menopause Vas... more >>omotor Symptoms Collapse << | Phase 3 | Completed | - | - |
| NCT00535288 | - | - | Completed | - | - |
| NCT00535288 | Postmenopausal Symptoms ... more >> Menopause Vasomotor Symptoms Collapse << | Phase 3 | Completed | - | - |
| NCT00506389 | Insomnia | Phase 3 | Completed | - | - |
| NCT00560833 | - | - | Completed | - | - |
| NCT00561821 | Insomnia Slee... more >>p Initiation and Maintenance Disorders Mental Disorders Dyssomnias Sleep Disorders Collapse << | Phase 3 | Completed | - | - |
| NCT00610675 | Insomnia | Phase 3 | Completed | - | - |
| NCT00561574 | - | - | Completed | - | - |
| NCT00561574 | Sleep Initiation and Maintenan... more >>ce Disorder; Elderly Mental Disorder Dyssomnias Sleep Disorders Sleep Disorder, Intrinsic Collapse << | Phase 3 | Completed | - | - |
| NCT00631657 | Sleep Initiation and Maintenan... more >>ce Disorders Mental Disorders Dyssomnias Sleep Disorders Sleep Disorder, Intrinsic Collapse << | Phase 3 | Completed | - | - |
| NCT00610675 | - | - | Completed | - | - |
| NCT00561821 | - | - | Completed | - | - |
| NCT00832520 | Advanced Cancer | Phase 2 | Terminated(Low accrual rate.) | - | United States, New Mexico ... more >> University of New Mexico Cancer Center @ Lovelace Medical Center Albuquerque, New Mexico, United States, 87102 Universtiy of New Mexico - Cancer Center Albuquerque, New Mexico, United States, 87106 Collapse << |
| NCT00834197 | Healthy | Phase 1 | Completed | - | United States, North Dakota ... more >> PRACS Institute, Ltd. Fargo, North Dakota, United States, 58104 Collapse << |
| NCT00832520 | - | - | Terminated(Low accrual rate.) | - | - |
| NCT00835575 | Healthy | Phase 1 | Completed | - | United States, North Dakota ... more >> PRACS Institute, Ltd. Fargo, North Dakota, United States, 58104 Collapse << |
| NCT00834197 | - | - | Completed | - | - |
| NCT00750919 | Sleep Initiation and Maintenan... more >>ce Disorders Mental Disorders Dyssomnias Sleep Disorders Sleep Disorders, Intrinsic Collapse << | Phase 3 | Terminated(This trial was stop... more >>ped prematurely due to the Sponsor's decision not to continue the development of esmertazapine for this indication.) Collapse << | - | - |
| NCT00835575 | - | - | Completed | - | - |
| NCT00750919 | - | - | Terminated(This trial was stop... more >>ped prematurely due to the Sponsor's decision not to continue the development of esmertazapine for this indication.) Collapse << | - | - |
| NCT00631657 | - | - | Completed | - | - |
| NCT00878540 | Healthy | Phase 1 | Completed | - | Germany ... more >> Max Planck Institue of Psychiatry Munich, Germany Collapse << |
| NCT00865696 | Healthy | Phase 1 | Completed | - | United States, North Dakota ... more >> PRACS Institute, Ltd. Fargo, North Dakota, United States, 58102 Collapse << |
| NCT00865384 | Healthy | Phase 1 | Completed | - | United States, North Dakota ... more >> PRACS Institute, Ltd. Fargo, North Dakota, United States, 58102 Collapse << |
| NCT00919295 | Fibromyalgia Syndrome | Phase 2 | Completed | - | Thailand ... more >> Siriraj Hospital, Mahidol University Bangkoknoi, Bangkok, Thailand, 10700 Collapse << |
| NCT01302964 | Autism Spectrum Disorders | Phase 3 | Completed | - | United States, Indiana ... more >> Riley Child and Adolescent Psychiatry Clinic Riley Hospital Indianapolis, Indiana, United States, 46202 United States, Massachusetts Lurie Center -MassGeneral Hospital Lexington, Massachusetts, United States, 02421 Collapse << |
| NCT01119924 | Depression Pa... more >>in Collapse << | Phase 4 | Completed | - | Taiwan ... more >> Nang Kuang Pharmaceutical Co., LTD Tainan, Xinhua Township, Taiwan Collapse << |
| NCT01302964 | - | - | Completed | - | - |
| NCT01039740 | Depression | Not Applicable | Unknown | December 2018 | Korea, Republic of ... more >> Samsung Medical Center Recruiting Kangnam, Seoul, Korea, Republic of, 135-710 Contact: Samsung Medical Center Kim, phD, MD 82-2-3410-3582 dohkwan.kim@samsung.com Collapse << |
| NCT00960830 | Depression An... more >>xiety Collapse << | Not Applicable | Completed | - | Argentina ... more >> Cl Sn Nicol San Nicolas, Bs As, Argentina, 1900 Collapse << |
| NCT01601002 | Major Depressive Disorder | Phase 4 | Completed | - | Canada, Ontario ... more >> London Health Sciences Centre London, Ontario, Canada, N6A 5W9 Collapse << |
| NCT01240096 | Functional Dyspepsia | Phase 4 | Unknown | December 2011 | Belgium ... more >> University Hospitals Recruiting Leuven, Vlaanderen, Belgium, 3000 Contact: Jan Tack, M.D., Ph.D. +3216344225 jan.tack@med.kuleuven.be Principal Investigator: Jan Tack, M.D., Ph.D. Collapse << |
| NCT01867775 | Alzheimer's Disease ... more >> Sleep Disorders Collapse << | Phase 3 | Unknown | May 2014 | Brazil ... more >> Brasilia University Recruiting Brasilia, Distrito Federal, Brazil, 70840 Contact: Francisca M Scoralick franciscascoralick@gmail.com Sub-Investigator: Francisca M Scoralick Collapse << |
| NCT02185131 | Major Depressive Disorder ... more >> Alcohol Use Disorder Collapse << | Phase 2 | Completed | - | United States, Pennsylvania ... more >> Western Psychiatric Institute and Clinic Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
| NCT01505504 | - | - | Completed | - | Belgium ... more >> CHU Brugmann Brussels, Belgium, 1020 Collapse << |
| NCT02228239 | Healthy | Phase 1 | Completed | - | Netherlands ... more >> Leiden, Netherlands Collapse << |
| NCT02185131 | - | - | Completed | - | - |
| NCT02646449 | - | - | Completed | - | - |
| NCT03031184 | Dementia | Phase 3 | Recruiting | July 2020 | United Kingdom ... more >> Sube Banerjee Recruiting Brighton, Sussex, United Kingdom, BN1 9RY Contact: Sube Banerjee, MD 01273877896 s.banerjee@bsms.ac.uk Principal Investigator: Naji Tabet, MD Principal Investigator: Chris Fox, MD Principal Investigator: Alan Thomas, MD Principal Investigator: Ross Dunne, MD Principal Investigator: Gill Livingston, MD Principal Investigator: Peter Bentham, MD Principal Investigator: Annabel Price, MD Principal Investigator: Ramin Nilforooshan, MD Principal Investigator: Carol Bannister, MD Principal Investigator: Sushanth Kamath, MD Collapse << |
| NCT03254173 | Advanced Cancer ... more >> Cancer Associated Anorexia - Cachexia Collapse << | Phase 2 Phase 3 | Not yet recruiting | August 1, 2018 | - |
| NCT01569685 | Post Traumatic Stress Disorder... more >> Depression Collapse << | Phase 4 | Completed | - | Denmark ... more >> Competence Center for Transcultural Psychiatry Gentofte, Denmark, 2900 Collapse << |
| NCT00917397 | Post-Traumatic Stress Disorder | Phase 4 | Completed | - | Denmark ... more >> Psykiatrisk Center Gentofte Hellerup, Denmark, 2900 Collapse << |
| NCT02650544 | Carcinoma, Non-Small-Cell Lung... more >> Depression Collapse << | Phase 2 | Active, not recruiting | June 2019 | China, Guangdong ... more >> Cancer Center of Sun-Yat Sen University (CCSYSU) GuangZhou, Guangdong, China, 510060 Collapse << |
| NCT02646449 | Major Depressive Disorder ... more >> Alcohol Use Disorder Collapse << | Phase 2 | Completed | - | United States, Pennsylvania ... more >> Western Psychiatric Institute and Clinic Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
| NCT02761161 | Post Traumatic Stress Disorder... more >> Depression Collapse << | Phase 4 | Active, not recruiting | March 2019 | Denmark ... more >> Competence Centre for Transcultural Psychiatry Copenhagen, Ballerup, Denmark, 2750 Collapse << |
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